Ellansé S — Polycaprolactone (PCL) Biostimulator with Immediate Volume & Long-Term Collagen

Ellansé S is a CE-certified bio-stimulating dermal filler from AQTIS Medical (Netherlands) that uniquely combines immediate structural volume with gradual, long-term collagen stimulation — making it one of the most versatile products in the biostimulator category.

What Is Ellansé S?

Ellansé S uses polycaprolactone (PCL) microspheres suspended in a carboxymethylcellulose (CMC) gel carrier. On injection, the CMC gel provides immediate, visible volume restoration. As the CMC is absorbed (over 3–4 months), the PCL microspheres remain in tissue, triggering sustained fibroblast activity and new collagen synthesis. Duration: ~12 months.

Technology & Formula

• PCL microspheres in CMC gel carrier — dual-action mechanism
• Immediate effect: CMC gel volume; long-term effect: PCL collagen stimulation
• CE-certified Class III medical device, AQTIS Medical
• Duration of results: ~12 months

Key Features

• Immediate volume + long-term collagen stimulation in one product
• Results that continue to improve as collagen forms
• Duration ~12 months — shorter duration — ideal for first-time biostimulator patients or younger patients with mild volume loss
• Non-reversible (PCL cannot be dissolved) — patient selection and technique are critical
• CE-certified, manufactured in Netherlands

Clinical Indications

Volume restoration of the midface, cheeks, and temples; correction of nasolabial folds and marionette lines; non-surgical chin and jawline refinement; and skin laxity improvement in the lower face.

How to Use

Inject into deep dermis or subcutaneous layer using bolus technique. Do not inject superficially. Product is not reversible — ensure correct depth and placement.

See also: Sculptra (https://frayamedsupply.com/us/product/sculptra) | Lanluma V (https://frayamedsupply.com/us/product/lanluma-v) | Biostimulators (https://frayamedsupply.com/us/category/biostimulators)