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Sculptra — Poly-L-Lactic Acid (PLLA) Collagen Biostimulator by Galderma

Sculptra is one of the most established and clinically proven collagen stimulators in aesthetic medicine. Approved in the US, extensively studied, and trusted by practitioners worldwide, it uses poly-L-lactic acid (PLLA) to trigger the body’s own collagen production — delivering results that are gradual, natural-looking, and remarkably long-lasting.

What Is Sculptra?

Sculptra is a CE-certified injectable filler manufactured by Sanofi/Galderma, containing microparticles of poly-L-lactic acid (PLLA) — a synthetic, biodegradable polymer with a well-established safety profile in medical and aesthetic use. PLLA microparticles are gradually absorbed, triggering fibroblast activation and new collagen synthesis over months.

Technology & Formula

  • Active ingredient: poly-L-lactic acid (PLLA) microparticles in sterile water
  • Mechanism: biocompatible microparticles trigger controlled collagen synthesis
  • Result timeline: improvement begins 4–8 weeks post-injection; full results at 3–6 months
  • Duration: up to 2 years with optimal protocol
  • CE-certified Class III medical device

Key Features

  • Long-lasting results — up to 24 months
  • Progressive, natural-looking improvement
  • Suitable for significant volume loss, skin laxity, and deep structural correction
  • Must be reconstituted according to protocol before use
  • Requires 2–3 sessions for optimal results

Clinical Indications

Significant facial volume loss (cheeks, temples, midface), skin laxity in the lower face and neck, deep nasolabial folds, and correction of HIV-related lipoatrophy. Also used diluted for large-area rejuvenation of the décolleté, arms, and hands.

How to Use

Reconstitute with sterile water (5–8ml minimum for facial use; more for body). Allow 24+ hours for full hydration. Inject into deep dermis or subcutaneous layer using bolus technique. Massage post-injection is essential. Space sessions 4–8 weeks apart.

See also: Ellansé M (https://frayamedsupply.com/us/product/ellanse-m) | Lanluma V (https://frayamedsupply.com/us/product/lanluma-v) | Biostimulators (https://frayamedsupply.com/us/category/biostimulators)

Composition

  • Poly-L-lactic acid (150mg)
  • Sodium carboxymethylcellulose (90mg)
  • Non-pyrogenic mannitol (127.5mg).

Contains

  • 2 Poly-L-lactic acid vials
  • Package inserts
  • 4 traceability labels

Sculptra

2 vials 150mg/ml

292.05$ Gross (incl. 0% VAT)

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For professional use only. Purchase confirms appropriate training and qualifications

Sculptra — Poly-L-Lactic Acid (PLLA) Collagen Biostimulator by Galderma

Sculptra is one of the most established and clinically proven collagen stimulators in aesthetic medicine. Approved in the US, extensively studied, and trusted by practitioners worldwide, it uses poly-L-lactic acid (PLLA) to trigger the body's own collagen production — delivering results that are gradual, natural-looking, and remarkably long-lasting.

What Is Sculptra?

Sculptra is a CE-certified injectable filler manufactured by Sanofi/Galderma, containing microparticles of poly-L-lactic acid (PLLA) — a synthetic, biodegradable polymer with a well-established safety profile in medical and aesthetic use. PLLA microparticles are gradually absorbed, triggering fibroblast activation and new collagen synthesis over months.

Technology & Formula

  • Active ingredient: poly-L-lactic acid (PLLA) microparticles in sterile water
  • Mechanism: biocompatible microparticles trigger controlled collagen synthesis
  • Result timeline: improvement begins 4–8 weeks post-injection; full results at 3–6 months
  • Duration: up to 2 years with optimal protocol
  • CE-certified Class III medical device

Key Features

  • Long-lasting results — up to 24 months
  • Progressive, natural-looking improvement
  • Suitable for significant volume loss, skin laxity, and deep structural correction
  • Must be reconstituted according to protocol before use
  • Requires 2–3 sessions for optimal results

Clinical Indications

Significant facial volume loss (cheeks, temples, midface), skin laxity in the lower face and neck, deep nasolabial folds, and correction of HIV-related lipoatrophy. Also used diluted for large-area rejuvenation of the décolleté, arms, and hands.

How to Use

Reconstitute with sterile water (5–8ml minimum for facial use; more for body). Allow 24+ hours for full hydration. Inject into deep dermis or subcutaneous layer using bolus technique. Massage post-injection is essential. Space sessions 4–8 weeks apart.

See also: Ellansé M (https://frayamedsupply.com/us/product/ellanse-m) | Lanluma V (https://frayamedsupply.com/us/product/lanluma-v) | Biostimulators (https://frayamedsupply.com/us/category/biostimulators)

Composition

  • Poly-L-lactic acid (150mg)
  • Sodium carboxymethylcellulose (90mg)
  • Non-pyrogenic mannitol (127.5mg).

Contains

  • 2 Poly-L-lactic acid vials
  • Package inserts
  • 4 traceability labels

Frequently Asked Questions

How many Sculptra sessions are needed?

Most patients require 2–3 sessions spaced 4–8 weeks apart. The number of vials per session depends on the degree of volume loss — typically 1–2 vials per session for facial treatment. Results continue to develop between sessions and for several months after the final treatment.

What is the most important aftercare instruction for Sculptra?

The 5-5-5 rule: massage the treated area 5 times per day, for 5 minutes, for 5 days post-treatment. This distributes the PLLA microparticles evenly in tissue and significantly reduces the risk of nodule formation.

How is Sculptra different from HA fillers?

HA fillers provide immediate volume by physically filling tissue — results are visible immediately and last 6–18 months. Sculptra works by stimulating your own collagen production — results develop over months and last up to 2 years. Sculptra is a better choice for patients seeking gradual, natural-looking improvement or who want longer-lasting results.

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