Dear Customers, Fräya will be off on 21st April, but don't worry you will still be able to make and order or write us a message! All orders made thru 19th till 21st will be shipped on 22nd April. Have a Happy Easter!
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Buy Nucleofill Soft Plus for Periocular Rejuvenation & Eye Area Enhancement

Buy Nucleofill Soft Plus, a cutting-edge bio-stimulator treatment designed to transform the delicate eye area. This advanced injectable solution combines highly purified polynucleotides at 15mg/2ml concentration to effectively address eye bags, periocular wrinkles, and tissue regeneration. When you buy Nucleofill Soft Plus, you’re choosing a professional-grade treatment that promotes natural collagen production and enhances skin hydration for lasting rejuvenation results. 

What is Nucleofill Soft Plus?

Nucleofill Soft Plus is a bio-stimulator treatment formulated for the delicate periocular area. This advanced injectable solution contains highly purified polynucleotides at a concentration of 15 mg per 2 ml, designed to address multiple concerns around the eye area. It promotes natural collagen and elastin production while enhancing skin hydration at a cellular level.

 

What makes this treatment unique is its non-crosslinked formula, which allows for seamless integration into the skin without adding volume. The product’s optimal viscoelasticity ensures precise administration and even distribution during treatment, making it particularly effective for addressing eye bags, periocular wrinkles, and skin laxity in the eye area.

What are the indications for Nucleofill Soft Plus treatment?

  • Treatment of eye bags and puffiness
  • Addressing periocular wrinkles
  • Re-densification of dermo-epidermal tissue
  • Bio-restructuring of deep tissues
  • Improvement of superficial wrinkles without fillers
  • Pre- and post-surgical treatment for procedures like blepharoplasty, lifting, and laser resurfacing

Nucleofill Soft Plus target areas

The treatment specifically targets the periocular area, which includes:

    • The delicate skin around the eyes
  • Under-eye region
  • Areas affected by fine lines and wrinkles surrounding the eyes
  • The complete eye contour area

Who is the manufacturer of Nucleofill Soft Plus?

Nucleofill products are manufactured by Promoitalia, an Italian company that specializes in medical aesthetics. They are known for developing innovative biotechnological products focused on skin rejuvenation and anti-ageing treatments.

Benefits and results of using Nucleofill Soft Plus

  • Activates natural collagen and elastin production, leading to firmer and smoother skin
  • Enhances skin moisture levels, creating a plump and refreshed appearance
  • Effectively reduces fine lines and wrinkles around the eye area
  • Protects against environmental factors that contribute to premature ageing
  • Delivers lasting improvements that become visible within weeks after treatment
  • Specifically designed for safe use in the sensitive periocular region
  • Results persist for 6-9 months with proper maintenance

Nucleofill Soft Plus main ingredients and device properties

  • Contains polynucleotides at a 15 mg / 2 ml concentration (7.5 mg/ml)
  • Features a molecular weight of approximately 50–100 KD
  • pH level between 6.8 and 7.2
  • Viscosity of 28-35 Pa*s
  • Non-crosslinked formula for natural tissue integration
  • Highly biocompatible composition
  • Optimal viscoelasticity for precise administration
  • Designed for fluid distribution during injection

Accessories or items included

Each package of Nucleofill Soft Plus contains:

  • 1 pre-filled sterile syringe (2 ml)
  • 2 sterile needles (30G, 12mm)
  • Product information leaflet with usage and aftercare instructions

Storage conditions

  • Store at a temperature between 2°C and 25°C
  • Avoid freezing the product
  • Keep away from direct sunlight
  • Store in a dry environment
  • Keep in original packaging until use

Mode of administration

The treatment follows a specific protocol:

  • Begin with thorough cleansing and disinfection of the treatment area
  • Optional topical anaesthetic application for patient comfort
  • Two main injection techniques:
  • Linear retrograde technique with cannula in the hypodermis for even distribution
  • Micro-porous technique for superficial treatments
  • Treatment schedule:
  • 2 initial sessions 14 days apart
  • Followed by 2 additional sessions 21 days apart

Post-treatment care

  • Avoid sun and UV exposure for 48 hours after treatment
  • No makeup application on treated areas for 24 hours
  • Maintain proper cleanliness and hydration of treated areas
  • Avoid strenuous exercise for 48 hours
  • Stay away from heat exposure for 48 hours

How long does Nucleofill Soft Plus last?

Results from Nucleofill Soft Plus treatments typically last for 6–9 months. To maintain optimal results, patients should consider follow-up maintenance treatments every 3–6 months to preserve the desired skin hydration and texture improvements.

Potential side effects

Common and temporary side effects:

  • Swelling or mild redness at injection sites
  • Bruising or tenderness in treated areas
  • Itching or slight discomfort where the product was administered

 

Rare but possible complications:

  • Allergic reactions
  • Infection
  • Vascular occlusion (extremely rare)

Contraindications for the treatment

Treatment should not be administered to patients with:

  • Pregnancy or during breastfeeding
  • Active skin infections or severe allergies
  • Autoimmune disorders
  • History of keloid scarring
  • Uncontrolled diabetes
  • Bleeding disorders
  • Recent cosmetic procedures
  • Specific skin conditions (such as eczema or rosacea)
  • Hypertrophy of the adipose panniculus in the lower eyelid area (fat bags)
  • Lower eyelid oedema (liquid bags)
  • Allergies to any components of the product

Who can buy Nucleofill Soft Plus and where?

Nucleofill products are medical-grade aesthetic treatments specifically developed for licensed healthcare professionals, including dermatologists, cosmetic doctors, and certified aesthetic practitioners. The specialised formulation and precise application requirements mean these products must only be administered by qualified medical professionals with appropriate training and expertise.

For those seeking to purchase Nucleofill, Fraya Med Supply stands as a trusted and authorized distributor of professional aesthetic products. When you source your dermal filler products through Fraya Med Supply, you’re guaranteed authentic products, optimal safety standards, and access to premium-quality treatments that fully comply with medical industry regulations.

Nucleofill Product Range

How much does Nucleofill cost?

The price of Neucelofill products ranges from £40 to £100 per package.

Is Nucleofill worth it? 

Based on extensive clinical results and patient experiences, Nucleofill treatments have proven highly effective for their intended applications. The treatment excels by stimulating the body’s regenerative mechanisms, delivering both instant and sustained improvements. While individual results may vary, as with all aesthetic procedures, the treatment consistently provides dependable outcomes when performed by qualified medical professionals, making it a valuable investment for those seeking skin rejuvenation.

How long does Nucleofill take to work?

Initial improvements can be noticed within the first few weeks following treatment. The bio-stimulating effects of Nucleofill continue to develop over time as the skin’s natural regenerative processes are activated. For optimal results, the recommended protocol includes:

  • 2 initial sessions spaced 14 days apart
  • Followed by 2 additional sessions at 21-day intervals
  • Full results typically become visible after completing the treatment protocol
  • Effects can last 6-9 months with proper maintenance sessions every 3-6 months

Composition

  • Gel with 2.5% polynucleotide concentration

Contains

  • 1 x 2ml prefilled syringe
  • 1 x sterile 30G 13 mm needles

Nucleofill Soft Plus

1 x 2ml prefilled syringe

Eyes area Hydration Lifting
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Remember, if you are a professional from the EU, we will ask you for your VAT number at the checkout.

Buy Nucleofill Soft Plus for Periocular Rejuvenation & Eye Area Enhancement

Buy Nucleofill Soft Plus, a cutting-edge bio-stimulator treatment designed to transform the delicate eye area. This advanced injectable solution combines highly purified polynucleotides at 15mg/2ml concentration to effectively address eye bags, periocular wrinkles, and tissue regeneration. When you buy Nucleofill Soft Plus, you're choosing a professional-grade treatment that promotes natural collagen production and enhances skin hydration for lasting rejuvenation results. 

What is Nucleofill Soft Plus?

Nucleofill Soft Plus is a bio-stimulator treatment formulated for the delicate periocular area. This advanced injectable solution contains highly purified polynucleotides at a concentration of 15 mg per 2 ml, designed to address multiple concerns around the eye area. It promotes natural collagen and elastin production while enhancing skin hydration at a cellular level.   What makes this treatment unique is its non-crosslinked formula, which allows for seamless integration into the skin without adding volume. The product's optimal viscoelasticity ensures precise administration and even distribution during treatment, making it particularly effective for addressing eye bags, periocular wrinkles, and skin laxity in the eye area.

What are the indications for Nucleofill Soft Plus treatment?

  • Treatment of eye bags and puffiness
  • Addressing periocular wrinkles
  • Re-densification of dermo-epidermal tissue
  • Bio-restructuring of deep tissues
  • Improvement of superficial wrinkles without fillers
  • Pre- and post-surgical treatment for procedures like blepharoplasty, lifting, and laser resurfacing

Nucleofill Soft Plus target areas

The treatment specifically targets the periocular area, which includes:
    • The delicate skin around the eyes
  • Under-eye region
  • Areas affected by fine lines and wrinkles surrounding the eyes
  • The complete eye contour area

Who is the manufacturer of Nucleofill Soft Plus?

Nucleofill products are manufactured by Promoitalia, an Italian company that specializes in medical aesthetics. They are known for developing innovative biotechnological products focused on skin rejuvenation and anti-ageing treatments.

Benefits and results of using Nucleofill Soft Plus

  • Activates natural collagen and elastin production, leading to firmer and smoother skin
  • Enhances skin moisture levels, creating a plump and refreshed appearance
  • Effectively reduces fine lines and wrinkles around the eye area
  • Protects against environmental factors that contribute to premature ageing
  • Delivers lasting improvements that become visible within weeks after treatment
  • Specifically designed for safe use in the sensitive periocular region
  • Results persist for 6-9 months with proper maintenance

Nucleofill Soft Plus main ingredients and device properties

  • Contains polynucleotides at a 15 mg / 2 ml concentration (7.5 mg/ml)
  • Features a molecular weight of approximately 50–100 KD
  • pH level between 6.8 and 7.2
  • Viscosity of 28-35 Pa*s
  • Non-crosslinked formula for natural tissue integration
  • Highly biocompatible composition
  • Optimal viscoelasticity for precise administration
  • Designed for fluid distribution during injection

Accessories or items included

Each package of Nucleofill Soft Plus contains:
  • 1 pre-filled sterile syringe (2 ml)
  • 2 sterile needles (30G, 12mm)
  • Product information leaflet with usage and aftercare instructions

Storage conditions

  • Store at a temperature between 2°C and 25°C
  • Avoid freezing the product
  • Keep away from direct sunlight
  • Store in a dry environment
  • Keep in original packaging until use

Mode of administration

The treatment follows a specific protocol:
  • Begin with thorough cleansing and disinfection of the treatment area
  • Optional topical anaesthetic application for patient comfort
  • Two main injection techniques:
  • Linear retrograde technique with cannula in the hypodermis for even distribution
  • Micro-porous technique for superficial treatments
  • Treatment schedule:
  • 2 initial sessions 14 days apart
  • Followed by 2 additional sessions 21 days apart

Post-treatment care

  • Avoid sun and UV exposure for 48 hours after treatment
  • No makeup application on treated areas for 24 hours
  • Maintain proper cleanliness and hydration of treated areas
  • Avoid strenuous exercise for 48 hours
  • Stay away from heat exposure for 48 hours

How long does Nucleofill Soft Plus last?

Results from Nucleofill Soft Plus treatments typically last for 6–9 months. To maintain optimal results, patients should consider follow-up maintenance treatments every 3–6 months to preserve the desired skin hydration and texture improvements.

Potential side effects

Common and temporary side effects:
  • Swelling or mild redness at injection sites
  • Bruising or tenderness in treated areas
  • Itching or slight discomfort where the product was administered
  Rare but possible complications:
  • Allergic reactions
  • Infection
  • Vascular occlusion (extremely rare)

Contraindications for the treatment

Treatment should not be administered to patients with:
  • Pregnancy or during breastfeeding
  • Active skin infections or severe allergies
  • Autoimmune disorders
  • History of keloid scarring
  • Uncontrolled diabetes
  • Bleeding disorders
  • Recent cosmetic procedures
  • Specific skin conditions (such as eczema or rosacea)
  • Hypertrophy of the adipose panniculus in the lower eyelid area (fat bags)
  • Lower eyelid oedema (liquid bags)
  • Allergies to any components of the product

Who can buy Nucleofill Soft Plus and where?

Nucleofill products are medical-grade aesthetic treatments specifically developed for licensed healthcare professionals, including dermatologists, cosmetic doctors, and certified aesthetic practitioners. The specialised formulation and precise application requirements mean these products must only be administered by qualified medical professionals with appropriate training and expertise. For those seeking to purchase Nucleofill, Fraya Med Supply stands as a trusted and authorized distributor of professional aesthetic products. When you source your dermal filler products through Fraya Med Supply, you're guaranteed authentic products, optimal safety standards, and access to premium-quality treatments that fully comply with medical industry regulations.

Nucleofill Product Range

How much does Nucleofill cost?

The price of Neucelofill products ranges from £40 to £100 per package.

Is Nucleofill worth it? 

Based on extensive clinical results and patient experiences, Nucleofill treatments have proven highly effective for their intended applications. The treatment excels by stimulating the body's regenerative mechanisms, delivering both instant and sustained improvements. While individual results may vary, as with all aesthetic procedures, the treatment consistently provides dependable outcomes when performed by qualified medical professionals, making it a valuable investment for those seeking skin rejuvenation.

How long does Nucleofill take to work?

Initial improvements can be noticed within the first few weeks following treatment. The bio-stimulating effects of Nucleofill continue to develop over time as the skin's natural regenerative processes are activated. For optimal results, the recommended protocol includes:
  • 2 initial sessions spaced 14 days apart
  • Followed by 2 additional sessions at 21-day intervals
  • Full results typically become visible after completing the treatment protocol
  • Effects can last 6-9 months with proper maintenance sessions every 3-6 months

Composition

  • Gel with 2.5% polynucleotide concentration

Contains

  • 1 x 2ml prefilled syringe
  • 1 x sterile 30G 13 mm needles

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