What is Mesotherapy All About?

Introduction

A treatment that can refresh your skin, reduce wrinkles, and even promote hair growth—all without surgery – that’s mesotherapy. Developed in France by Dr. Michel Pistor in the 1950s,¹ mesotherapy started as a pain relief method but has since transformed into a cornerstone of aesthetic medicine.

Mesotherapy is a safe procedure with minimal injections where a mix of vitamins, enzymes, hormones, and plant extracts are usually injected into the mesoderm (the middle layer of your skin). This technique delivers nutrients directly to the skin to enhance its health and appearance from within.

But what makes mesotherapy truly exciting? It’s the versatility. Whether you’re looking to smooth out fine lines, hydrate your skin, reduce cellulite, or even stimulate hair growth, mesotherapy has a solution. It’s not just about looking good; it’s about nourishing your skin with the essential ingredients it craves.

This treatment has become a favorite in aesthetic medicine because it offers visible results without the downtime or risks associated with surgery. It can address a variety of concerns, right from improving skin texture to localized fat reduction.

If you are looking to understand mesotherapy better, this guide will help you understand how it works, its benefits, and its uses. Whether your goal is to achieve a radiant glow, combat the signs of aging, or address stubborn fat deposits, this article will equip you with the knowledge needed to make an informed decision.

What Is Mesotherapy?

Mesotherapy involves injecting different compounds like vitamins, enzymes, hormones, or plant extracts directly into the skin. This injection therapy tries to rejuvenate and tighten the skin, and it can also help remove excess fat. Essentially, mesotherapy provides targeted nutrient delivery to address specific skin problems.

The word “mesotherapy” cleverly combines two Greek words: “mesos,” meaning middle, and “therapeia,” which translates to medical treatment.

This kind of targeted nutrient delivery helps address issues like poor circulation and inflammation that contribute to skin damage and aging.

It is performed in certain regions of the body such as:

Face and neck.
Arms
Thighs, buttocks, hips, legs.
Abdomen (the stomach region).
Scalp

Mesotherapy is versatile and used for a variety of aesthetic procedures. It can improve skin texture and hydration, reduce fine lines and wrinkles, and even combat hair loss and cellulite. This makes it a popular choice for those looking to enhance their overall skin health and appearance.

To see how much this technique is gaining popularity across the world, a report by Future Market Insights revealed some interesting insights:

· In 2021, people spent $134.2 million on mesotherapy treatments worldwide.

· By 2032, this number is expected to grow to $768 million.

· This means the market is growing by about 17.5% each year.

These numbers show that more and more people are choosing mesotherapy for their skin and beauty treatments. It’s becoming a big part of the beauty industry and will likely keep growing in the coming years.

How Does Mesotherapy Work?

Mesotherapy works by delivering tiny amounts of specially formulated solutions directly into the skin. Let’s break down the process to understand how this innovative technique achieves its results:

Precise Delivery:

During mesotherapy, small amounts of special solutions are injected directly into the mesoderm. This layer has tiny blood vessels, so the ingredients stay concentrated at the treatment site for a long time.

Customized Solutions:

The solutions used in mesotherapy are tailored to each patient’s needs. These “cocktails” contain a mix of vitamins, minerals, enzymes, antioxidants, and amino acids. These solutions are designed to be safe for the body and target specific skin concerns.

Gentle Injections:

Very fine needles are used for mesotherapy, with different techniques for different goals. Superficial injections target the upper skin layers for overall rejuvenation. In contrast, deeper injections can address issues like cellulite or localized fat deposits.

Slow Absorption:

The effectiveness of mesotherapy lies in its slow absorption. The injections are made into areas with small blood vessels, which prevents rapid absorption and allows the ingredients to remain in the targeted area longer.

Natural Time-Release:

Once injected, the skin acts as a natural time-release system for the medication, keeping the solutions within the targeted space for an extended period.⁴

Stimulating Healing:

The tiny injections stimulate the skin and help it heal naturally. They also encourage collagen and elastin production, producing firmer and more elastic skin.

Better Skin Quality:

The active substances in mesotherapy solutions help improve skin texture and hydration and reduce fine lines and wrinkles. Many patients experience “mesolifting,” which increases skin firmness for a mild lifting effect.

It’s important to note that the exact process of mesotherapy can vary depending on the specific concern being treated and the formulation used. Your healthcare provider can give you detailed information on how mesotherapy will work for your particular situation.

Benefits of Mesotherapy

Mesotherapy is beneficial in both cosmetic and therapeutic contexts. This minimally invasive technique offers significant advantages in skin rejuvenation, hydration, and overall skin health.

Improved Skin Texture and Hydration

One of the primary benefits of mesotherapy is its ability to enhance skin texture and hydration. Through the injection of a moisturizing substance called hyaluronic acid, along with vitamins and amino acids into your skin, collagen and elastin production is stimulated. This results in a natural lift and glow.

This leads to a more supple and smooth texture. According to scientists, the localized delivery of these nutrients boosts collagen and elastin production, which are crucial for maintaining skin elasticity and firmness.

Reduction of Fine Lines and Wrinkles

Apart from rejuvenating the skin, mesotherapy injections also boost new collagen and elastin production, two proteins that give the skin a youthful appearance. The Italian Society of Mesotherapy’s consensus report highlights that. This treatment can significantly diminish wrinkles and fine lines by plumping the skin and improving its structure. This process not only smoothens existing lines but also helps to prevent the formation of new ones.

Brightens Skin

Mesotherapy can tackle dullness, uneven skin tone, and loss of elasticity all at once. Compared to regular skincare products, mesotherapy helps achieve a brighter, more even complexion and overall skin vitality.

Hydration Boost

Think of hyaluronic acid as your skin’s natural moisturizer. When used in mesotherapy, it keeps your skin hydrated and plump, giving you that dewy, radiant look everyone loves. It’s perfect for maintaining that fresh, youthful glow.

Customizable Treatments

One of the best things about mesotherapy is that it’s customizable. Whether you’re dealing with acne scars or pigmentation issues, or just want overall skin rejuvenation, the ingredients can be tailored to meet your specific needs. This means you get a treatment that’s just right for you.

Minimal Downtime

Unlike other cosmetic procedures, mesotherapy has minimal downtime. Most people can go back to their normal activities shortly after the treatment. This makes it a great option for those with busy schedules who want effective skincare solutions without a big time commitment.

Safe and Minimally Invasive

Safety is a big plus with mesotherapy. When done by qualified professionals, it’s generally safe with a low risk of complications, especially compared to more invasive procedures.

Common Uses of Mesotherapy

Pain Management

Mesotherapy is not just about aesthetics; it’s also effective for managing localized pain, including musculoskeletal pain, arthritis, and sports injuries. By injecting anti-inflammatory medications and muscle relaxants directly into the affected area, it provides significant pain relief. Plus, it helps reduce the need for systemic medications, making it a beneficial option for those suffering from chronic pain conditions.

Cosmetic Applications

Besides hair loss, cellulite, facial rejuvenation, and pain management, mesotherapy finds great value in other cosmetic applications. It can be used to:

Even out skin tone and reduce dark spots by targeting melanin deposits in the skin
Mesotherapy can help in reducing the appearance of scars by promoting healing and regeneration of the skin.
Reduce your stretch marks by increasing collagen production.

While the benefits are many, it is important to have realistic expectations. Also, multiple sessions may be required to get the kind of results you want. Consulting with a qualified professional can help decide the best treatment plan for you.

Mesotherapy for Hair Loss

How Mesotherapy Helps with Hair Regrowth

This involves small injections into your scalp, about 1 to 4 mm deep. The goal is to wake up your dormant hair follicles, boost blood flow, and encourage new hair growth.

This method can be particularly effective if you’re dealing with androgenetic alopecia, where your hair follicles are often weakened. Recent studies have shown that this approach not only promotes new hair growth but also strengthens your existing hair and reduces thinning.³

Some research suggests that combining mesotherapy with other treatments like minoxidil and dutasteride might work even better than using these treatments on their own.^6,7 This combination approach could improve both your hair density and overall scalp health.

Your results will depend on factors like how much hair you’ve lost, your overall health, and how well you stick to the treatment plan. We’ll work together to create the best approach for you.

Mesotherapy for Cellulite Reduction

Here’s How Mesotherapy Targets Cellulite

For cellulite reduction, these injections typically contain fat-breaking agents (lipolytic agents) that help dissolve fat cells and improve blood flow.⁴

· It breaks down fat in specific areas, which helps reduce the dimpled look of cellulite.

· It boosts blood flow and helps your body get rid of toxins and extra fluids that can make cellulite worse.

· It stimulates your body to make more collagen and elastin, which helps your skin look firmer and smoother over time.

· It improves lymphatic drainage, removes broken-down fat, and reduces swelling.

Expected Results and Duration

You’ll likely start seeing improvements in your cellulite after a few sessions. Your skin should look smoother and firmer as we go along.

Most people need about 4-10 treatments, usually 1-2 weeks apart. This can change based on how your body responds.

To keep your results looking good, try to include regular exercise and a balanced diet.

The good news is you can usually get back to your normal activities right after each treatment. You might have some mild redness or swelling where we did the injections, but this typically goes away within a few hours to days.

What to Expect During a Mesotherapy Session?

Understanding what happens during a mesotherapy process can help you feel more at ease and prepared for your treatment. Let’s walk through what a typical session entails and what you might experience before, during, and after the procedure.

Before Your Session

The process begins with an initial consultation. This is your opportunity to discuss your goals and any concerns with your practitioner. They’ll assess your suitability for mesotherapy and explain the procedure in detail. Do open up about your medical history to ensure the treatment is safe for you.²

Before starting mesotherapy, your doctor will take their time to conduct a detailed evaluation of your physical and mental health. It usually involves the following:

· Review your health history and do a quick check-up.

· Discuss your reasons for wanting this treatment.

· Check for allergies, pregnancy, skin issues, or immune concerns.

· Ask about past treatments you’ve tried.

· Take measurements to track your progress.

· Take “before” photos.

Your doctor will give you a realistic idea of what to expect. You must know that mesotherapy isn’t FDA-approved in the US.

If this treatment doesn’t meet your expectations, your doctor can suggest other non-surgical options or surgery.

Remember, you’re welcome to ask questions at any point in this process.

During your session

On the day of your treatment:

Preparation: The treatment area will be thoroughly cleaned to prevent infection. If needed, a topical anesthetic may be applied to ensure your comfort.
The Procedure: A fine needle (typically 1 to 4 millimeters in depth) is used to inject a tailor-made solution of vitamins, enzymes, hormones, or medications into the middle layer of your skin. Doctors may use techniques such as “nappage” (multiple small injections) or “point-by-point” (deeper injections at specific points).
Sensation: You might feel a slight pricking sensation or mild discomfort during the injections. Most patients find this quite manageable, even with multiple injections throughout the treatment area.
Duration: Sessions typically last between 30 to 60 minutes, depending on the size of the treatment area and specific techniques used.

Here’s what you can do to make the best of your post-session care:

Redness, minor bruising, or swelling at the injection sites are normal reactions and usually subside within a few days. Use a cold to reduce the swelling.
Your practitioner will provide specific aftercare instructions. These may include avoiding strenuous activities, hot showers, and direct sun exposure for 48 hours. Keeping the treated area clean and dry can help prevent infection.
There’s minimal downtime, so you can usually resume normal activities shortly after treatment. However, it’s advisable to rest and avoid heavy exercise for a day or two.
For optimal results, you’ll likely need multiple sessions, typically spaced a week to a month apart. Your practitioner will create a personalized treatment schedule for you.
While you might see some improvements after the first session, significant changes typically become noticeable after a few treatments. These changes can vary based on your condition and response to the therapy.

Remember, everyone’s experience can vary slightly. If you have any concerns during or after your treatment, don’t hesitate to reach out to your healthcare provider. They’re there to ensure your comfort and safety throughout the mesotherapy process.

Side Effects and Risks of Mesotherapy

When performed by a qualified cosmetic specialist, mesotherapy is generally safe. But like any medical procedure, it has its share of potential side effects and risks.^2,3 Here’s what you need to know to manage these concerns effectively:

Common Side Effects and How to Manage Them

· Some pain or discomfort where you were injected. This usually goes away within a day. You can use cold packs and over-the-counter pain relievers to help.

· Redness and swelling at the injection sites. This usually takes a few days to clear up. Keep the area clean and avoid too much heat or sun.

· Bruising that may last up to a week. To help prevent this, avoid blood thinners before your treatment unless your doctor says otherwise.

· Itching or irritation, which is usually temporary. Your doctor may recommend antihistamines or creams to help.

· In rare cases, infection can occur. To avoid this, make sure your treatment is done in a clean environment by a licensed professional.

· Allergic reactions are possible. Do remember to inform your doctor about any allergies you have in advance.

· Some people might see changes in skin color, especially those with darker skin. Using sunscreen after treatment can help.

· Very rarely, skin tissue can die if the injections aren’t done properly.

· Repeated treatments might cause scar tissue or lumps under the skin.

Safety Precautions and Risk Management

Choose a Qualified Practitioner: Ensure that your mesotherapy is performed by a licensed and experienced medical professional. Verify their credentials and ask about their experience with mesotherapy.
Follow Pre- and Post-Treatment Instructions: The complications you experience can be reduced by following guidelines provided by your practitioner both before and after the procedure. This includes avoiding certain medications, keeping the treated area clean, and attending all follow-up appointments.

Before undergoing mesotherapy, ensure that you fully understand the procedure, its potential risks, and the expected outcomes. Your practitioner will share detailed information and answer any questions you may have.

Who Is a Good Candidate for Mesotherapy?

Mesotherapy can be an excellent option for many, but it’s might not suitable for some. If you’re in good overall health and looking for a gentle yet effective way to enhance your natural beauty, mesotherapy might be your new best friend.

Here is a list of who might benefit most from this treatment and who should consider alternatives.²

Healthy Individuals:

You should generally be in good health and free from chronic conditions that might complicate the procedure.

Realistic Expectations:

It’s important to understand what mesotherapy can and cannot do. This means knowing that the results may be different for everyone, but it can offer noticeable benefits.

Specific Aesthetic Concerns:

Mesotherapy is a great option for specific beauty goals, such as:

If you want smoother, more hydrated skin and fewer fine lines.
If you’re dealing with hair loss.
Reducing the appearance of cellulite through targeted fat reduction.
For reducing localized fat deposits and contouring specific areas of your body.
If you prefer non-surgical, minimally invasive treatments with minimal downtime.

Commitment to Multiple Sessions:

Mesotherapy usually requires several sessions to achieve the best results. So, it’s important that you’re willing to commit to a full treatment plan for best results.

When Should You Avoid Mesotherapy:

Here are the conditions where mesotherapy is contraindicated, and your doctor may defer treatment.

Pregnant or breastfeeding women
Individuals with chronic skin conditions or active infections.
Those with autoimmune disorders or blood clotting issues.
People with severe allergies to mesotherapy ingredients.
Patients undergoing cancer treatment.
Individuals with poorly controlled diabetes.

Every case is unique. That’s why a pre-treatment consultation with a qualified professional is essential. During this chat, you’ll have the opportunity to:

Discuss your medical history and any concerns.
Have a physical examination of the areas you’d like treated.
Talk about your goals and set realistic expectations.
Undergo any necessary allergy tests and bloodwork.

Conclusion

The rise of mesotherapy isn’t a fad. Several factors are driving its popularity in the beauty world. More and more people in their middle years are looking for ways to keep their youthful glow.

This demand is being met by a growing number of aesthetic clinics offering mesotherapy treatments. Medical tourism for cosmetic procedures is also on the rise. But what makes mesotherapy so appealing are its benefits. It’s all about affordability and convenience. Unlike some expensive and invasive procedures, mesotherapy is a budget-friendly and readily available option.

The potential results of mesotherapy are indeed promising. But what works wonderfully for one person may yield different results for another.

Smaller studies haven’t always shown significant benefits. For instance, one study with a limited number of participants didn’t find improvement in wrinkles after mesotherapy for skin rejuvenation. Additionally, another study involving body contouring didn’t show a reduction in thigh size.⁵

The wide variety of ingredients and techniques used in mesotherapy treatments can also make it hard to definitively measure its overall effectiveness. To understand its potential benefits and drawbacks more clearly, we need larger-scale, long-term studies.

This is why we strongly encourage you to seek expert recommendations before going ahead.

Consulting with a qualified practitioner will help them create a personalized treatment plan that is in line with your specific goals and concerns. This will ensure you get the most out of your mesotherapy sessions.

Also, remember that mesotherapy is just one among many cosmetic procedures. It can even be combined with other treatments or lifestyle changes for optimal results.

References

El-Domyati M, El-Ammawi TS, Moawad O, El-Fakahany H, Medhat W, Mahoney MG, Uitto J. Efficacy of mesotherapy in facial rejuvenation: a histological and immunohistochemical evaluation. Int J Dermatol. 2012 Aug;51(8):913-9. doi: 10.1111/j.1365-4632.2011.05184.x. PMID: 22788806; PMCID: PMC3513770.
Madhere S, ed. Aesthetic Mesotherapy and Injection Lipolysis in Clinical Practice. Illustrated edition. Taylor & Francis; 2007. ISBN: 1841845531, 9781841845531.
Sivagnanam G. Mesotherapy – The french connection. J Pharmacol Pharmacother. 2010 Jan;1(1):4-8. doi: 10.4103/0976-500X.64529. PMID: 21808584; PMCID: PMC3142757.
Saluja, Harish & Patil, Ajinkya & Shah, Seemit & Dadhich, Anuj & Sachdeva, Shivani. (2020). Mesotherapy: Overview. IP International Journal of Maxillofacial Imaging. 6. 29-32. 10.18231/j.ijmi.2020.008.
Park SH, Kim DW, Lee MA, Yoo SC, Rhee SC, Koo SH, Seol GH, Cho EY. Effectiveness of mesotherapy on body contouring. Plast Reconstr Surg. 2008 Apr;121(4):179e-185e. doi: 10.1097/01.prs.0000304611.71480.0a. PMID: 18349597.
Gajjar PC, Mehta HH, Barvaliya M, Sonagra B. Comparative Study between Mesotherapy and Topical 5% Minoxidil by Dermoscopic Evaluation for Androgenic Alopecia in Male: A Randomized Controlled Trial. Int J Trichology. 2019 Mar-Apr;11(2):58-67. doi: 10.4103/ijt.ijt_89_18. PMID: 31007474; PMCID: PMC6463458.
Nestor MS, Ablon G, Gade A, Han H, Fischer DL. Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics. J Cosmet Dermatol. 2021 Dec;20(12):3759-3781. doi: 10.1111/jocd.14537. Epub 2021 Nov 6. PMID: 34741573; PMCID: PMC9298335.