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Karisma

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We would like to introduce you to Karisma, a new biostimulator that stimulates the body to regenerate and create collagen or elastin fibers. As you know, collagen and elastin fibers are of key importance for the elasticity and quality of the skin.

Karisma is a biostimulator based on recombinant human collagen obtained from silkworm breeding. The knowledge of the gene sequence for one of the silk proteins, sericin, made it possible to replace it with the type I collagen gene. As a result of this replacement, silkworms synthesize collagen, which, when injected into the skin, improves the condition of the extracellular matrix (ECM).

What sets Karisma apart is that it contains only natural ingredients without chemical cross-linking agents. It is 100% bioavailable and mobilizes the skin to bioregeneration, making it safe and does not cause allergic reactions. Karisma is a class III medical device, biostimulator and soft filler, which includes Type I collagen α1 polypeptide chain, CMC – carboxymethylcellulose, and HA – high molecular weight hyaluronic acid.

The collagen contained in Karisma is obtained using innovative technology with the use of silk threads, and it is not of animal origin. Thanks to the NEOSILK technology, the production of type I procollagen C-peptide in fibroblasts increases. This type of peptide facilitates the wrapping of procollagen molecules into a triple helix (superhelis) conformation in the endoplasmic reticulum. CMC has anti-aging properties, reduces the activity of free oxygen radicals and endogenous hyaluronidase, and has a protective effect against hyaluronic acid. Finally, HA gives an immediate post-treatment effect and improves the quality of the extracellular matrix and promotes the migration of fibroblasts.

The effects of using Karisma are impressive. It rejuvenates the skin of the face, mouth, neck, cleavage, and hands, improves the face contour, has a gentle lifting effect, reduces wrinkles, scars and stretch marks, and improves the quality and density of the skin.

The Karisma protocol is based on the performance of 2 treatments with an interval of 1 month. Depending on the age, lifestyle, and skin quality, the effects of the treatment last from 6 to 12 months. It is worth doing a booster treatment after 4 months. Depending on the indications, Karisma is administered by mesotherapy or linear retrograde technique, using a needle or cannula. The procedure does not require anesthesia or convalescence.

It is important to note that Karisma is a product for professional use only. By deciding to purchase, you declare that you are a doctor or cosmetologist trained in aesthetic medicine.

In conclusion, Karisma is a natural, biocompatible, and safe product that offers quick and natural effects in the form of firming, tightening, and improving the quality of the skin. We highly recommend Karisma to our medical professional colleagues who want to provide their patients with the latest and most innovative treatments available.

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